Search results for alzheimers

New research from the University of South Carolina is uncovering exactly how non-alcoholic fatty liver disease (NAFLD) influences the neurological conditions associated with Alzheimer’s disease. The study describes how a certain protein produced in the liver can travel to the brain and trigger neuroinflammation.Continue ReadingCategory: ScienceTags: Alzheimer's Disease, Dementia, Neuroscienc
New imaging research is offering detailed insights into the relationship between Alzheimer’s disease and abnormal accumulations of iron in the brain. The study confirms a distinct correlation between higher iron deposits in particular brain regions and rates of cognitive decline.Continue ReadingCategory: ScienceTags: Alzheimer's Disease, Dementia, Neuroscience, fMRI, Brain, Medical Imaging
A detailed new brain imaging study, examining a number of cognitively healthy middle-aged subjects, is suggesting lower levels of estrogen in women post-menopause could play a role in triggering brain changes linked to Alzheimer’s disease. The research hypothesizes this mechanism may be one of the reasons why women suffer from Alzheimer’s at greater rates than men.Continue ReadingCategory: Scienc
Researchers in Germany have discovered a new mechanism by which Alzheimer’s disease impairs memory recall – and, importantly, found a way to reverse it in mice. Neurons encoded with existing memories are being drowned out by noise from neurons encoding new experiences, and silencing these allowed the mice to regain lost memories.Continue ReadingCategory: Medical, ScienceTags: Alzheimer's Dis
Encouraging results from a small Phase 2 human trial testing the effects of a cancer drug in treating Alzheimer’s disease have been published in the journal Annals of Neurology. The data suggests the drug is safe, well-tolerated and alters biomarkers associated with Alzheimer’s. A larger efficacy study is currently planned.Continue ReadingCategory: Medical, ScienceTags: Alzheimer's Disease,
Two new studies, published in the journal The Lancet Neurology, are suggesting increasing levels of a particular brain protein, detected in blood and spinal fluid, could be the earliest sign of neurodegenerative diseases such as Alzheimer’s and Huntington’s.Continue ReadingCategory: Medical, ScienceTags: Alzheimer's Disease, Neuroscience, Dementia, Brain, Diagnosis, University College London
An international team of scientists has designed a novel antibody that can accurately detect the toxic oligomers suspected to cause the neurodegeneration associated with Alzheimer’s disease. It's hoped the breakthrough will lead to improved drug design and clinical testing by offering researchers a new way to measure these protein aggregations.Continue ReadingCategory: ScienceTags: Alzheimer&apos
There are many unknowns when it comes to the complex mechanisms underpinning Alzheimer's disease, but research is continuing to shine a light on some of the key suspects. A new mouse study from Massachusetts General Hospital has for the first time established a connection between elevated levels of calcium in mitochondria and neuron death associated with the disease, offering a potential new targ
New evidence has been published in the journal Science Advances, adding weight to the link between Alzheimer’s disease and the common herpes virus. The Tufts University study, using a 3D bioengineered brain model, demonstrated how a herpes infection can induce a number of Alzheimer’s features, including neuroinflammation and amyloid plaques.Continue ReadingCategory: ScienceTags: Alzheimer's
While its exact causes are unknown, Alzheimer’s disease is commonly associated with clumps of toxic amyloid plaques in the brain, and researchers are continuing to understand the different components that help them take shape. Scientists at the University of Illinois at Urbana-Champaign have developed a new compound that attacks a number of the key players in the formation of amyloid plaques, sig


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